产品货号：
Z35010
中文名称：
Laminin Alpha 4/LAMA4抗体
英文名称：
Anti-Laminin Alpha 4/LAMA4 Antibody (Clone#OTI5G8)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Laminin Alpha 4/LAMA4 Antibody (Clone#OTI5G8) |
| 指标别名 | LAMA4 (Isoform 3);Laminin 14 subunit alpha;Laminin 8 subunit alpha;Laminin 9 subunit alpha;Laminin subunit alpha 4;laminin;alpha 4 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | LAMA4 |
| 克隆号 | OTI5G8 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Human recombinant protein fragment corresponding to amino acids 25-270 of human LAMA4(NP_001098676) produced in E.coli. |
| 实际分子量 | 199.8KD |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | Laminins,a family of extracellular matrix glycoproteins,are the major noncollagenous constituent of basement membranes.They have been implicated in a wide variety of biological processes including cell adhesion,differentiation,migration,signaling,neurite outgrowth and metastasis.Laminins are composed of 3 non identical chains:laminin alpha,beta and gamma (formerly A,B1,and B2,respectively) and they form a cruciform structure consisting of 3 short arms,each formed by a different chain,and a long arm composed of all 3 chains.Each laminin chain is a multidomain protein encoded by a distinct gene.Several isoforms of each chain have been described.Different alpha,beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery,i.e.alpha1beta1gamma1 heterotrimer is laminin 1.The biological functions of the different chains and trimer molecules are largely unknown,but some of the chains have been shown to differ with respect to their tissue distribution,presumably reflecting diverse functions in vivo.This gene encodes the alpha chain isoform laminin,alpha 4.The domain structure of alpha 4 is similar to that of alpha 3,both of which resemble truncated versions of alpha 1 and alpha 2,in that approximately 1,200 residues at the N-terminus (domains IV,V and VI) have been lost.Laminin,alpha 4 contains the C-terminal G domain which distinguishes all alpha chains from the beta and gamma chains.The RNA analysis from adult and fetal tissues revealed developmental regulation of expression,however,the exact function of laminin,alpha 4 is not known.Tissue-specific utilization of alternative polyA-signal has been described in literature.Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq,Aug 2011] |
| Uniprot ID | Q16363 |
| 基因名全称 | Laminin subunit alpha-4 |
| 推荐稀释比 | Western blot (WB) 1:2000 Immunohistochemistry in paraffin section (IHC) 1:150 |
相关搜索：Laminin Alpha 4/LAMA4抗体，Laminin Alpha 4抗体，LAMA4单抗